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Vitamin D - Why You are Probably Not Getting Enough
___________________________________________ Studies Find Increasing Health Benefits From Vitamin D VOANEWs.com
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Vitamin D Vital for the Immune System
Dr. Mark Hyman
drhyman.com
Sott.net
Sat, 27 Aug 2011
© drhyman.com
What vitamin do we need in amounts up to 25 times higher than the government recommends for us to be healthy?
What vitamin deficiency affects over half of the population, is almost never diagnosed, and has been linked to many cancers, high blood pressure, heart disease, diabetes, depression,
fibromyalgia, chronic muscle pain, bone loss, and autoimmune diseases like multiple sclerosis?
What vitamin is almost totally absent from our food supply?
What vitamin is the hidden cause of so much suffering that is so easy to treat?
The answer to all of these questions is vitamin D.
Over the last 10 years of my practice, my focus has been to discover what the body needs to function optimally. And I have become more interested in the role of specific nutrients as the years have passed.
Two recent studies in the journal Pediatrics found that 70 percent of American kids aren't getting enough vitamin D, and this puts them at higher risk of obesity, diabetes, high blood pressure, and lower levels of good cholesterol. Low vitamin D levels also may increase a child's risk of developing heart disease later in life.
Overall, 7.6 million, or 9 percent, of U.S. children were vitamin-D deficient, and another 50.8 million, or 61 percent, had insufficient levels of this important vitamin in their blood.
Over the last 5 years, I have tested almost every patient in my practice for vitamin D deficiency, and I have been shocked by the results. What's even more amazing is what happens when my patients' vitamin D status reaches optimal levels. Having witnessed these changes, there's no doubt in my mind: vitamin D is an incredible asset to your health.
That is why in today's blog I want to explain the importance of this essential vitamin and give you 6 tips on how to get optimize your vitamin D levels.
Let's start by looking at the massive impact vitamin D has on the health and function of every cell and gene in your body.
How Vitamin D Regulates Your Cells and Genes
Vitamin D has a huge impact on the health and function of your cells. It reduces cellular growth (which promotes cancer) and improves cell differentiation (which puts cells into an anti-cancer state). That makes vitamin D one of the most potent cancer inhibitors - and explains why vitamin D deficiency has been linked to colon, prostate, breast and ovarian cancer.
But what's even more fascinating is how vitamin D regulates and controls genes.
It acts on a cellular docking station called a receptor that then sends messages to our genes. That's how vitamin D controls so many different functions - from preventing cancer, reducing inflammation, boosting mood, easing muscle aches and
fibromyalgia, and building bones.
These are just a few examples of the power of vitamin D. When we don't get enough it impacts every area of our biology, because it affects the way our cells and genes function. And many of us are deficient for one simple reason ...
Your body makes vitamin D when it's exposed to sunlight. In fact, 80 to 100 percent of the vitamin D we need comes from the sun. The sun exposure that makes our skin a bit red (called 1 minimum erythemal dose) produces the equivalent of 10,000 to 25,000 international units
(IU) of vitamin D in our bodies.
The problem is that most of us aren't exposed to enough sunlight.
Overuse of sunscreen is one reason. While these product help protect against skin cancer - they also block a whopping 97 percent of your body's vitamin D production.
If you live in a northern climate, you're not getting enough sun (and therefore vitamin D), especially during winter. And you're probably not eating enough of the few natural dietary sources of vitamin D: fatty wild fish like mackerel, herring, and cod liver oil.
Plus, aging skin produces less vitamin D - the average 70 year-old person creates only 25 percent of the vitamin D that a 20 year-old does. Skin color makes a difference, too. People with dark skin also produce less vitamin D. And I've seen very severe deficiencies in Orthodox Jews and Muslims who keep themselves covered all the time.
With all these causes of vitamin D deficiency, you can see why supplementing with enough of this vitamin is so important. Unfortunately, you aren't really being told the right amount of vitamin D to take.
The government recommends 200 to 600 IU of vitamin a day. This is the amount you need to prevent rickets, a disease caused by vitamin D deficiency. But the real question is: How much vitamin D do we need for OPTIMAL health? How much do we need to prevent autoimmune diseases, high blood pressure,
fibromyalgia, depression, osteoporosis, and even cancer?
The answer is: Much more than you think.
Recent research by vitamin D pioneer Dr. Michael Holick, Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine, recommends intakes of up to 2,000 IU a day - or enough to keep blood levels of 25 hydroxy vitamin D at between 75 to 125
nmol/L (nanomoles per liter). That may sound high, but it's still safe: Lifeguards have levels of 250
nmol/L without toxicity.
Our government currently recommends 2,000 IU as the upper limit for vitamin D - but even that may not be high enough for our sun-deprived population! In countries where sun exposure provides the equivalent of 10,000 IU a day and people have vitamin D blood levels of 105 to 163
nmol/L, autoimmune diseases (like multiple sclerosis, type 1 diabetes, inflammatory bowel disease, rheumatoid arthritis, and lupus) are uncommon.
Don't be scared that amounts that high are toxic: One study of healthy young men receiving 10,000 IU of vitamin D for 20 weeks showed no toxicity.
The question that remains is: How can you get the right amounts of vitamin D?
6 Tips for Getting the Right Amount of Vitamin D
Unless you're spending all your time at the beach, eating 30 ounces of wild salmon a day, or downing 10 tablespoons of cod liver oil a day, supplementing with vitamin D is essential. The exact amount needed to get your blood levels to the optimal range (100 to160
nmol/L) will vary depending on your age, how far north you live, how much time you spend in the sun, and even the time of the year. But once you reach optimal levels, you'll be amazed at the results.
For example, one study found that vitamin D supplementation could reduce the risk of getting type 1 diabetes by 80 percent. In the Nurses' Health Study (a study of more than 130,000 nurses over 3 decades), vitamin D supplementation reduced the risk of multiple sclerosis by 40 percent.
I've seen many patients with chronic muscle aches and pains and fibromyalgia who are vitamin D deficient - a phenomenon that's been documented in studies. Their symptoms improve when they are treated with vitamin D.
Finally, vitamin D has been shown to help prevent and treat osteoporosis. In fact, it's even more important than calcium. That's because your body needs vitamin D to be able to properly absorb calcium. Without adequate levels of vitamin D, the intestine absorbs only 10 to 15 percent of dietary calcium. Research shows that the bone-protective benefits of vitamin D keep increasing with the dose.
So here is my advice for getting optimal levels of vitamin D:
1. Get tested for 25 OH vitamin D. The current ranges for "normal" are 25 to 137
nmol/L or 10 to 55 ng/ml. These are fine if you want to prevent rickets - but NOT for optimal health. In that case, the range should be 100 to 160
nmol/L or 40 to 65 ng/ml. In the future, we may raise this "optimal" level even higher.
You can see now why I feel so passionately about vitamin D. This vitamin is critical for good health. So start aiming for optimal levels - and watch how your health improves.
2. Take the right type of vitamin D. The only active form of vitamin D is vitamin D3
(cholecalciferol). Look for this type. Many vitamins and prescriptions of vitamin D have vitamin D2 - which is not biologically active.
3. Take the right amount of vitamin D. If you have a deficiency, you should correct it with 5,000 to 10,000 IU of vitamin D3 a day for 3 months - but only under a doctor's supervision. For maintenance, take 2,000 to 4,000 IU a day of vitamin D3. Some people may need higher doses over the long run to maintain optimal levels because of differences in vitamin D receptors, living in northern latitudes, indoor living, or skin color.
4. Monitor your vitamin D status until you are in the optimal range. If you are taking high doses (10,000 IU a day) your doctor must also check your calcium, phosphorous, and parathyroid hormone levels every 3 months.
5. Remember that it takes up to 6 to 10 months to "fill up the tank" for vitamin D if you're deficient. Once this occurs, you can lower the dose to the maintenance dose of 2,000 to 4,000 Units a day.
6. Try to eat dietary sources of vitamin D. These include:
* Fish liver oils, such as cod liver oil. 1 TBSP (15 ml) = 1,360 IU of vitamin D
* Cooked wild salmon. 3.5 oz = 360 IU of vitamin D
* Cooked mackerel. 3.5 oz = 345 IU of vitamin D
* Sardines, canned in oil, drained. 1.75 oz = 250 IU of vitamin D
* One whole egg = 20 IU of vitamin D
Now I'd like to hear from you ...
Have you experienced any symptoms of vitamin D deficiency?
Do you think you are not getting enough sun?
Have you experienced any health benefits from getting more sun or correcting a vitamin D deficiency you may have had?
Please share your thoughts by leaving a comment here.
To your good health,
Mark Hyman, MD
Carol Pearson | Washington 28 May 2010
Michael Irwig gives staff lectures on Vitamin D at George Washington University Hospital
Michael Irwig gives staff lectures on Vitamin D
at George Washington University Hospital
The U.S. Institute of Medicine is involved in a study that will likely result in an increase in the recommended daily intake of vitamin D. Research shows vitamin D affects nearly every area of the body and low levels of vitamin D can have serious consequences.
It's the vitamin associated with the sun that we absorb through our skin, and increasingly block out when we use sunblock, to avoid getting skin cancer.
Vitamin D is also available in some foods, but as the world gets fatter, Vitamin D gets trapped in body fat.
What doctors are now discovering is that many people don't have enough vitamin D.
That's why Dr. Michael Irwig gives lectures on Vitamin D to the staff at the George Washington University Hospital.
"Vitamin D has become a very hot topic in medicine now as we are discovering very high levels of vitamin D deficiency in our population, not only in the U.S., but worldwide," said Dr. Irwig.
Vitamin D helps our bodies absorb calcium and helps form and maintain strong bones. Extreme vitamin D deficiency causes deformities in children and weak bones in adults.
Doctors rarely see these conditions. But studies have linked vitamin D deficiency to a number of serious health problems, including heart disease, several types of cancer, osteoporosis, diabetes, Alzheimer's disease and some autoimmune disorders.
Low levels of vitamin D are even associated with high blood pressure.
"What's very interesting about vitamin D is that it's involved all throughout the body, and it's involved on a local level, so you can have vitamin D active in the breasts, in the prostate, in the colon, and it's thought that the locally-acting vitamin D is helping to protect the body against these cancers, regulating how cells grow and how cells
die," added Dr. Irwig.
Doctors are also finding connections between vitamin D and pregnancy.
"There have been some studies showing that if you give pregnant women 4,000 units of vitamin D a day, their rates of complications in pregnancy are much decreased," noted Dr. Irwig. "If you look at things like infection, pre-term delivery, even gestational diabetes mellitus, they are all reduced with
giving pregnant women higher doses of vitamin D."
The Institute of Medicine, which advises the U.S. government on health, is expected to update its recommended amount of vitamin D by September.
It currently recommends 200 to 600 units of vitamin D daily. But many experts, including Dr. Irwig, recommend adults take 1,000 to 2,000 units a day, an amount only possible to get though
supplements.
Reuters
Last updated 10:56 08/03/2010
http://www.stuff.co.nz/life-style/wellbeing/
3417910/Vitamin-D-vital-for-immune-system
Chuck the chair - and lose weight Are germs making you fat? Who are the worst drivers? The formula for wedded bliss Stop judging my lunch Making yourself eat Mid to late 20s best age for first baby - poll Intimidating gym instructors Are friends sabotaging your diet?
Vitamin D is vital in activating human defences and low levels suffered by around half the world's population may mean their immune systems' killer T cells are poor at fighting infection, scientists said.
The findings by Danish researchers could help the fight against infectious diseases and global epidemics, they said, and could be particularly useful in the search for new vaccines.
The researchers found that immune systems' killer cells, known as T cells, rely on vitamin D to become active and remain dormant and unaware of the possibility of threat from an infection or pathogen if vitamin D is lacking in the blood.
"When a T cell is exposed to a foreign pathogen, it extends a signalling device or 'antenna' known as a vitamin D receptor, with which it searches for vitamin D," said Carsten Geisler of Copenhagen University's department of international health, immunology and microbiology, who led the study.
"This means the T cell must have vitamin D or activation of the cell will cease. If the T cells cannot find enough vitamin D in the blood, they won't even begin to mobilise."
Scientists have known for a long time that vitamin D is important for calcium absorption, and that there is a link between levels of the vitamin and diseases such as cancer and multiple sclerosis.
"What we didn't realise is how crucial vitamin D is for actually activating the immune system - which we know now," Geisler wrote in the study in the journal Nature Immunology.
Most Vitamin D is made by the body as a natural by-product of the skin's exposure to sunlight. It can also be found in fish liver oil, eggs and fatty fish such as salmon, herring and mackerel, or taken as a supplement.
Almost half of the world's population has lower than optimal levels of vitamin D and scientists say the problem is getting worse as people spend more time indoors.
Geisler and his research team said the findings offered much needed information about the immune system and would be of particular use when developing new vaccines.
"This is important not only in fighting disease but also in dealing with anti-immune reactions of the body and the rejection of transplanted organs," they wrote.
Active T cells multiply at an explosive rate and as well as fighting infection, can also mistakenly attack the body itself.
After and an organ transplant, for example, T cells can attack the new organ as a "foreign invader", and in autoimmune disease, hypersensitive T cells mistake parts of the body's own cells as threats, prompting the body to attack itself.
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Geisler said there were no definitive studies on the optimal daily vitamin D dose but experts recommend 25 to 50 micrograms.
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